MOTIVATED PROTEINS is a web facility devoted to a range of small hydrogen-bonded motifs, such as Beta Turns, Schellman Loops and Beta Bulges, which are common constituents of the three-dimensional structure of proteins. The ‘Motif Glossary’ lists the available motifs and provides a comprehensive definition of each of them. The ‘Introduction’ section provides illustrations of the facilities available, bibliographic and author information, and links to software and data downloads.
Most users will be interested either in a particular protein or a particular motif. For any of the 430 proteins in the database you can search for individual or overlapping motifs in that protein, and motifs near ligands or active sites. If you are interested in a particular motif, ‘Specific Motifs’ gives you access to all the examples of that motif in the database.
A key feature of Motivated Proteins is the ability to view the three-dimensional structure of motifs and their hydrogen bonding. This is now provided by JSmol — the HTML5 version of the venerable Jmol. As JSmol does not requires Java, you can now view the structures on your iPad (or even on your iPhone). You do, however, need to use a modern web browser — one that can handle HTML5 (see ‘Help’).